URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=31705
Proper Citation: RRID:MMRRC_031705-UCD
Description: Mus musculus with name C57BL/6J-Slfn2m1Btlr/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Immunology and Inflammation, Research Tools; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix
Phenotype: increased neutrophil cell number [MP:0000219]| decreased monocyte cell number [MP:0000223]| abnormal T cell activation [MP:0001828]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal leukocyte physiology [MP:0002442]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| increased T cell apoptosis [MP:0006413]| decreased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008079]| decreased CD8-positive [MP:0009788]| alpha-beta T cell number [MP:0009791]
Affected Gene: Slfn2
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)