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URL: https://web.expasy.org/cellosaurus/CVCL_4W79
Proper Citation: JCRB Cat# JCRB1564, RRID:CVCL_4W79
Description: Cell line TMNK-1 is a Transformed cell line with a species of origin Homo sapiens (Human)
Sex: Female
Defining Citation: PMID:15167590
Comments: Characteristics: Transduced with two retroviral vectors: 1) SSR#197 (MoMLV/LTR-LoxP-hTERT-IRES-EGFP-LoxP-MoMLV/LTR) expressing hTERT and eGFP flanked by two loxP sites and 2) SSR#69 (MoMLV/LTR-LoxP-HygroR-HSV/TK-IRES-SV40T-LoxP-Neo-MoMLV/LTR) expressing HygroR, HSV-1 TK and SV40 T-antigen flanked by two loxP sites., Characteristics: Because it has been transduced by two constructs containing LoxP sites, transfection with the Cre recombinase eliminates both the SV40 T gene and TERT thus reverting the cells to a non-immortal phenotype., Group: Patented cell line.
Category: Transformed cell line
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Source: Cellosaurus
