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URL: https://web.expasy.org/cellosaurus/CVCL_E7IX
Proper Citation: RRID:CVCL_E7IX
Description: Cell line HeLa Luc/705 is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Female
Disease: Human papillomavirus-related endocervical adenocarcinoma
Defining Citation: PMID:9572837
Comments: Characteristics: Transfected with a construct containing a luciferase gene interrupted by a mutated human beta-globin intron 2, HBB IVS2-705. The mutation in the intron causes aberrant splicing of luciferase pre-mRNA, preventing translation of luciferase. However, treatment of the cells with a 2'-O-methyl-oligoribonucleotide targeted to the aberrant splice sites induces correct splicing, restoring luciferase activity (PubMed=9572837)., Population: African American.
Category: Cancer cell line
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Source: Cellosaurus
