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URL: https://web.expasy.org/cellosaurus/CVCL_Z631
Proper Citation: RRID:CVCL_Z631
Description: Cell line HC-04 is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Male
Disease: Hepatoblastoma
Defining Citation: PMID:16687667, PMID:17590308, PMID:22990793, PMID:24532842, PMID:29370800, PMID:30891005
Comments: Population: Caucasian., Problematic cell line: Possibly contaminated. Indicated (PubMed=24532842) to have a near genetic identity with Hep-G2 cells. But they are functionally different from Hep-G2 cells since they support sporozoite invasion and liver stage exoerythrocytic development of Plasmodium falciparum and Plasmodium vivax. But STR profile from BEI Resources is identical to that of Hep-G2. Originally thought to originate from the spontaneous immortalization of a normal liver tissue of an hepatoma patient.., Group: Patented cell line., Group: Malaria research cell line.
Category: Cancer cell line
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No rating or validation information has been found for HC-04.
Possibly Contaminated
Problematic cell line: Possibly contaminated. Indicated (PubMed=24532842) to have a near genetic identity with Hep-G2 cells. But they are functionally different from Hep-G2 cells since they support sporozoite invasion and liver stage exoerythrocytic development of Plasmodium falciparum and Plasmodium vivax. But STR profile from BEI Resources is identical to that of Hep-G2.
Possibly Contaminated
Problematic cell line: Possibly contaminated. Indicated (PubMed=24532842) to have a near genetic identity with Hep-G2 cells. But they are functionally different from Hep-G2 cells since they support sporozoite invasion and liver stage exoerythrocytic development of Plasmodium falciparum and Plasmodium vivax. But STR profile from BEI Resources is identical to that of Hep-G2.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-3441.
Discontinued
Discontinued: ATCC; PTA-3441
Source: Cellosaurus
