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URL: https://web.expasy.org/cellosaurus/CVCL_LB02
Proper Citation: RRID:CVCL_LB02
Description: Cell line PathHunter U2OS OPRM1 Total GPCR Internalization is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Female
Disease: Osteosarcoma
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Category: Cancer cell line
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Source: Cellosaurus
