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URL: http://www.addgene.org/183825
Proper Citation: RRID:Addgene_183825
Insert Name: pgRNAs targeting 166 lncRNAs and 874 pc-genes
Organism: Homo sapiens
Bacterial Resistance: Ampicillin
Defining Citation: PMID:35619054
Vector Backbone Description: Backbone Marker:Addgene #78534; Vector Backbone:pDECKO-mCherry; Vector Types:Lentiviral, CRISPR; Bacterial Resistance:Ampicillin
Comments: BLaER1 pgRNA CRISPR library is a CRISPR-Cas9 library to target lncRNAs and protein coding genes with a potential role in B-cell to macrophage transdifferentiation. It can be a resource to perform knockout screens in other models, such as macrophage differentiation. It is a knockout library with paired guide RNAs targeting both lncRNAs and protein coding genes. The backbone does not contain Cas9. It can be used with Cas9-expressing plasmids pLentiCas9-BFP (Addgene 78545) or pLentiCas9-T2A-BFP (Addgene 78547).
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Source: Addgene
