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Plasmid Name
pLZ12Km2-P23R:TA:Xen5
RRID:Addgene_88902 RRID Copied  
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RRID:Addgene_88902
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Plasmid Information

URL: http://www.addgene.org/88902

Proper Citation: RRID:Addgene_88902

Insert Name: toxin-antitoxin + LuxABCDE

Organism: Synthetic

Bacterial Resistance: Kanamycin

Defining Citation: PMID:24061415

Vector Backbone Description: Backbone Marker: Nobuhiko Okada (PMID: 9846743); Vector Backbone:pLZ12Km2; Vector Types:Bacterial Expression; Bacterial Resistance:Kanamycin

Comments: This plasmid contains a toxin-antitoxin system that stabilizes the plasmid in Streptococcus by post-segregational killing of bacteria that have lost the plasmid. This stabilization improves plasmid utility in animal infection models. For more information, please see the original reference. Although designed for use with Streptococcus pyogenes, this plasmid also labels other streptococcal species. For more information, please see Loh JM and Proft T (2016). PMID: 26410784

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Ratings and Alerts

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Data and Source Information

Source: Addgene