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URL: http://www.bioconductor.org/packages/release/bioc/html/QDNAseq.html
Proper Citation: QDNAseq (RRID:SCR_003174)
Description: Software package for quantitative DNA sequencing for chromosomal aberrations providing a robust, cost-effective WGS method for DNA copy number analysis. The genome is divided into non-overlapping fixed-sized bins, number of sequence reads in each counted, adjusted with a simultaneous two-dimensional loess correction for sequence mappability and GC content, and filtered to remove spurious regions in the genome. Downstream steps of segmentation and calling are also implemented via packages DNAcopy and CGHcall, respectively.
Synonyms: QDNAseq - Quantitative DNA sequencing for chromosomal aberrations
Resource Type: software resource
Defining Citation: PMID:25236618
Keywords: software package, unix/linux, mac os x, windows, r, copy number variation, dna-seq, genetics, genome annotation, preprocessing, quality control, sequencing, bio.tools
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