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URL: http://supfam.mbu.iisc.ernet.in/index.html
Proper Citation: SUPFAM (RRID:SCR_005304)
Description: SUPFAM is a database that consists of clusters of potentially related homologous protein domain families, with and without three-dimensional structural information, forming superfamilies. The present release (Release 3.0) of SUPFAM uses homologous families in Pfam (Version 23.0) and SCOP (Release 1.69) which are examples of sequence -alignment and structure classification databases respectively. The two steps involved in setting up of SUPFAM database are * Relating Pfam and SCOP families using a new profile-profile alignment algorithm AlignHUSH. This results in identifying many Pfam families which could be related to a family or superfamily of known structural information. * An all-against-all match among Pfam families with yet unknown structure resulting in identification of related Pfam families forming new potential superfamilies. The SUPFAM database can be used in either the Browse mode or Search mode. In Browse mode you can browse through the Superfamilies, Pfam families or SCOP families. In each of these modes you will be presented with a full list which can be easily browsed. In Search mode, you can search for Pfam families, SCOP families or Superfamilies based on keywords or SCOP/Pfam identifiers of families and superfamilies.
Abbreviations: SUPFAM
Resource Type: data or information resource, database
Defining Citation: PMID:15113407, PMID:11752317
Keywords: duf/upf connections, 3-d structure, alignment, amino acid sequence, bioinformatics, clustering, homologous protein family, multiple sequence alignment, nmr, pali, pfam, phylogeny, protein classification, protein domain database, protein families, protein sequence database, rps_blast, scop, structural genomics, structure determination, superfamily, three-dimensional, x-ray crystalography
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