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URL: http://www.crash.lshtm.ac.uk/TP_English_StudyDesgn.htm
Proper Citation: CRASH (RRID:SCR_000221)
Description: Portal for placebo controlled trial of the effects of 48-hour infusion of corticosteroids on death and on neurological disability, among adults with head injury and some impairment of consciousness. The outcomes will be measured by rates of death and neurological disability. Patients are recruited (or entered by their doctors when informed consent is not obtainable due to impaired cognitive functioning) on a case-by-case basis as head injured patients come through emergency departments. Randomization is done via a 24-hour telephone line that will denote which pack of medication (either the corticosteroids or saline solution as control) to give.
Resource Type: topical portal, data or information resource, portal
Defining Citation: PMID:15936423
Keywords: corticosteroid, neurological disability, death, head injury, consciousness, randomized controlled trial, coma, clinical trial,
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