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NET-PD (Neuroprotection Exploratory Trials in PD): Futility Study I (RRID:SCR_001153)Copy Citation Copied
URL: https://parkinsontrial.ninds.nih.gov/about.htm
Proper Citation: NET-PD (Neuroprotection Exploratory Trials in PD): Futility Study I (RRID:SCR_001153)
Description: THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. This site has a dataset from a multicenter, double-blind, futility study of minocycline and creatine in subjects with early untreated Parkinson's Disease (PD) or FS-I (Futility Study I). There were 65 subjects/treatment arm with 195 total randomized subjects from approximately 42 sites in the US and Canada. A NINDS funded study. A Multicenter, Double-Blind, Futility Study of Minocycline and Creatine in subjects with early untreated Parkinson's Disease (PD) (FS-1).The primary objective of the study was to assess the impact of minocycline and creatine on the progression of PD in order to assess whether it was non-futile to proceed with further study of these agents. The progression of PD was measured by the change in total UPDRS score between the baseline visit and month 12 or the time of sufficient disability to require symptomatic therapy (last visit before subject goes on dopaminergic therapy), whichever occurs first. The additional follow-up of subjects until 18 months addressed the secondary objectives. The FS-1 study was conducted by the NINDS funded Neuroprotection Exploratory Trials in PD (NET-PD).
Synonyms: FS-1
Resource Type: database, data or information resource
Defining Citation: PMID:18520981
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