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URL: http://www.ebi.ac.uk/imgt/hla/
Proper Citation: IMGT/HLA (RRID:SCR_002971)
Description: Database for sequences of the human major histocompatibility complex (HLA) and includes the official sequences for the WHO Nomenclature Committee For Factors of the HLA System. It currently contains 9,310 allele sequences (2013) along with detailed information concerning the material from which the sequence was derived and data on the validation of the sequences. It is established procedure for authors to submit the sequences directly to the IMGT/HLA Database for checking and assignment of an official name prior to publication, this avoids the problems associated with renaming published sequences and the confusion of multiple names for the same sequence. The need for reasonably rapid publication of new HLA allele sequences has necessitated an annual meeting of the WHO Nomenclature Committee for Factors of the HLA System. Additionally they now publish monthly HLA nomenclature updates both in journals and online to provide quick and easy access to new sequence information. The IMGT/HLA Database is part of the international ImMunoGeneTics project. In collaboration with the Imperial Cancer Research Fund (ICRF) and European Bioinformatics Institute (EBI) they have developed an Oracle database to house the HLA sequences in such a way as to allow users to present complex queries about the sequence, sequence features, references, contacts and allele designations to the database via a graphical user interface over the web. The IMGT/HLA Database Submission Tool allows direct submission of sequences to the WHO HLA Nomenclature Committee for Factors of the HLA System. The IMGT/HLA Database provides an FTP site for the retrieval of sequences in a number of pre-formatted files.
Abbreviations: IMGT HLA, IMGT/HLA
Synonyms: IMGT HLA, IMGT/HLA DB, IMGT/HLA Database, International ImMunoGeneTics/Human Leukocyte Antigen Database
Resource Type: data or information resource, storage service resource, service resource, database, data repository
Defining Citation: PMID:21071412, PMID:10777106, PMID:18838392
Keywords: alignment, allele, cell, hla, sequence alignment, major histocompatibility complex, nomenclature, blast, immunogenetics, histocompatibility, gene mapping, gene rearrangement, genetic recombination, genetics, gold standard, bio.tools
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