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URL: http://gemdock.life.nctu.edu.tw/3D-Interologs
Proper Citation: 3D-Interologs (RRID:SCR_003101)
Description: Database of physical protein-protein interactions across multiple genomes. Based on 3D-domain interolog mapping and a scoring function, protein-protein interactions are inferred by using three-dimensional (3D) structure heterodimers to search the UniProt database. For a query protein, the database utilizes BLAST to identify homologous proteins and the interacting partners from multiple species. Based on the scoring function and structure complexes, it provides the statistic significances, the interacting models (e.g. hydrogen bonds and conserved amino acids), and functional annotations of interacting partners of a query protein. The identification of orthologous proteins of multiple species allows the study of protein-protein evolution, protein functions, and cross-referencing of proteins.
Abbreviations: 3D-interologs
Resource Type: data or information resource, analysis service resource, service resource, production service resource, database, data analysis service
Defining Citation: PMID:21143789
Keywords: interolog, protein-protein interaction, blast, homolog, protein, interaction, function
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