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URL: http://okcam.cbi.pku.edu.cn/ontology.php
Proper Citation: CAMO - Cell Adhesion Molecule Ontology (RRID:SCR_004392)
Description: CAMO (Cell Adhesion Molecule Ontology) is a set of standard vocabulary that provide a hierarchical description of cell adhesion molecules and their functions. We compiled a list for cell adhesion molecules by integrating Gene Ontology annotations, domain structure information, and keywords query against NCBI Entrez Gene annotations. Totally 496 unique human genes were identified to function as cell adhesion molecules, which is by far the most comprehensive dataset including cadherin, immunoglobulin/FNIII, integrin, neurexin, neuroligan, and catenin families. CAMO was constructed as a directed acyclic graph (DAG) using DAG-Edit to input, manage and update data. We annotated each term with name, definition and source references, as well as the relationship to other terms, based on manual reviews of domain architecture and functional annotations. If vertices represent terms and the relationships between terms are represented by edges, the terms in a DAG can be connected via a directed graph without cycles. CAMO thus provides a hierarchical description of functions of CAMs with five top-level categories: CAM gene families, CAM genetics, CAM regulation, CAM expression and CAM diseases. Each top-level term is further divided into several categories to describe the functions in detail.
Abbreviations: CAMO
Synonyms: Cell Adhesion Molecule Ontology
Resource Type: controlled vocabulary, data or information resource, ontology
Keywords: cell adhesion, molecule, function, cell adhesion molecule
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OKCAM: Ontology-based Knowledgebase for Cell Adhesion Molecules |
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