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Proper Citation: MLTreeMap (RRID:SCR_004792)
Description: Data analysis service that analyzes DNA sequences and determines their most likely phylogenetic origin. Its main use is in metagenomics projects, where DNA is isolated directly from natural environments and sequenced (the organisms from which the DNA originates are often entirely undescribed). It will search such sequences for suitable marker genes, and will use maximum likelihood analysis to place them in the ''''Tree of Life''''. This placement is more reliable than simply assessing the closest relative of a sequence using BLAST. More importantly, MLTreeMap decides not only who is the closest relative of your query sequence, but also how deep in the tree of life it probably branched off. Additionally, MLTreeMap searches the sequences for genes, which are coding for key enzymes of important functional pathways, such as RuBisCo, methane monooxygenase or nitrogenase. In case of a positive hit, MLTreeMap uses maximum likelihood analysis to place them in the respective ''''gene-family tree''''.
Abbreviations: MLTreeMap
Synonyms: Phylogenetic analysis of metagenomics sequence data
Resource Type: service resource, analysis service resource, production service resource, data analysis service
Defining Citation: PMID:20687950
Keywords: phylogeny, gene, fasta, dna sequence, nucleotide sequence, metagenomics, metagenome, bio.tools
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Source: SciCrunch Registry
