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URL: http://clip.med.yale.edu/SHM
Proper Citation: Models of SHM Targeting and Substitution (RRID:SCR_005250)
Description: A targeting model that defines where mutations occur (by specifying the relative rates at which DNA motifs in the Ig sequence are mutated), and a nucleotide substitution model that defines the resulting mutation (by specifying the probability of each base mutating to each of the other three possibilities as a function of the surrounding bases).
Abbreviations: S5F
Synonyms: S5F - Models of SHM Targeting and Substitution, Models of SHM Targeting and Substitution
Resource Type: data set, data or information resource
Defining Citation: PMID:24298272
Keywords: somatic hypermutation, substitution, targeting, aid, b cell, affinity maturation, immunoglobulin, mutability, mutation, model, targeting model, nucleotide substitution model
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