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URL: http://compbio.cs.brown.edu/projects/gasv/
Proper Citation: GASVPro (RRID:SCR_005259)
Description: Software tool combining both paired read and read depth signals into probabilistic model which can analyze multiple alignments of reads. Used to find structural variation in both normal and cancer genomes using data from variety of next-generation sequencing platforms. Used to predict structural variants directly from aligned reads in SAM/BAM format.Combines read depth information along with discordant paired read mappings into single probabilistic model two common signals of structural variation. When multiple alignments of read are given, GASVPro utilizes Markov Chain Monte Carlo procedure to sample over the space of possible alignments.
Abbreviations: GASVPro
Synonyms: GASVPro: Geometric Analysis of Structural Variants
Resource Type: software resource, software application, sequence analysis software, data analysis software, data processing software
Defining Citation: PMID:22452995
Keywords: structural variation, genome, genomics, alignment, sequencing, variant, variation, detection, dna, paired, end, read, sequence
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