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URL: http://hfv.lanl.gov/content/index
Proper Citation: HFV Database (RRID:SCR_006017)
Description: The Hemorrhagic Fever Viruses (HFV) sequence database collects and stores sequence data and provides a user-friendly search interface and a large number of sequence analysis tools, following the model of the highly regarded and widely used Los Alamos HIV database. The database uses an algorithm that aligns each sequence to a species-wide reference sequence. The NCBI RefSeq database is used for this; if a reference sequence is not available, a Blast search finds the best candidate. Using this method, sequences in each genus can be retrieved pre-aligned. Hemorrhagic fever viruses (HFVs) are a diverse set of over 80 viral species, found in 10 different genera comprising five different families: arena-, bunya-, flavi-, filo- and togaviridae. All these viruses are highly variable and evolve rapidly, making them elusive targets for the immune system and for vaccine and drug design. About 55,000 HFV sequences exist in the public domain today. A central website that provides annotated sequences and analysis tools will be helpful to HFV researchers worldwide.
Abbreviations: HFV Database
Synonyms: HFV Sequence Database, Hemorrhagic Fever Viruses Database, Hemorrhagic Fever Viruses (HFV) Database, LANL hemorrhagic fever virus database, Hemorrhagic Fever Viruses (HFV) Database Project
Resource Type: data or information resource, analysis service resource, service resource, production service resource, database, data analysis service
Defining Citation: PMID:22064861
Keywords: gene, hemorrhagic fever virus, biothreat, virus, sequence, nucleotide sequence, reference sequence, bio.tools
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