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URL: http://p53.fr
Proper Citation: UMD p53 Mutation Database (RRID:SCR_006720)
Description: The UMD TP53 Mutation Database is a novel web site exclusively dedicated to mutant TP53. The following datasets, analytical tools and software are available. * The TP53 UMD mutation database in human cancer (2012 release). This novel release (35,000 mutations, 3,600 publications) has been highly curated using an original and novel statistical procedure (See Edlung et al. PNAS 2012). * TP53MUTLOAD (MUTant Loss Of Activity Database), a novel database dedicated to detailed analysis of the properties of each TP53 mutant, ranging from transactivation to cell growth properties, change of conformation, localization or various gains of functions. The database contains more than 110,000 different entries. * TP53 Mut assessor, a novel stand-alone software available for both Windows and Mac users. Check your favorite TP53 mutants and get an instant identity card. Very useful to analyze any newly discovered TP53 mutants, as the software checks for every possible TP53 mutation. * MUT-TP53 2.0, an accurate and powerful tool that automatically manages p53 mutations and generate tables ready for publication, decreasing the risk of typing errors. MUT-TP53 2.0 also provides specific information for each TP53 mutation, allowing the user to assess the quality of the data. Up to 500 TP53 mutations can be managed simultaneously.
Abbreviations: p53 Database
Synonyms: UMD TP53 Mutation Database, UMD p53 Database, TP53 UMD mutation database
Resource Type: software resource, data or information resource, software application, database, data processing software
Defining Citation: PMID:22628563
Keywords: cell, dominant, germline, monoclonal, mutant, mutation, oncogene, p53, phylogenetic, polymorphism, prognosis, somatic, suppression, transform, tumor, tumorigenesis, umd, cell line
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