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T-One weighted Perfusion imaging Parameter CAlculation Toolkit (RRID:SCR_007376)Copy Citation Copied
URL: http://dblab.duhs.duke.edu/modules/dblabs_topcat/index.php
Proper Citation: T-One weighted Perfusion imaging Parameter CAlculation Toolkit (RRID:SCR_007376)
Description: TOPPCAT stands for T-One weighted Perfusion imaging Parameter CAlculation Toolkit. TOPPCAT creates quantitative maps of Ktrans (volume transfer constant between blood plasma and the extravascular extracellular space) and fPV (fractional plasma volume) from dynamic T1-weighted perfusion images. At the current time, analysis using the method of Patlak plots (most appropriate for first pass dynamic contrast-enhanced MR imaging) is supported. As a preliminary step for the parameter calculation, TOPPCAT also creates maps of T1 and S0 (equilibrium magnetization) from multi-flip angle T1-weighted SPGR (or FLASH) sequences.Daniel P. Barboriak, James R. MacFall, Anthony O. Padua,Gerald E. York, Benjamin L. Viglianti, and Mark W. Dewhirst. Standardized software for calculation of Ktrans and vp from dynamic T1-weighted MR images. Presented at the International Society for Magnetic Resonance in Medicine Workshop on MR in Drug Development: From Discovery to Clinical Therapeutic Trials, McLean VA, April 2004.
Synonyms: TOPPCAT
Resource Type: data processing software, software resource, image processing software, software application
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