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URL: http://epsf.bmad.bii.a-star.edu.sg/cube/db/html/home.html
Proper Citation: Cube-DB (RRID:SCR_013233)
Description: Cube-DB is a database of pre-evaluated conservation and specialization scores for residues in paralogous proteins belonging to multi-member families of human proteins. Protein family classification follows (largely) the classification suggested by HUGO Gene Nomenclature Committee. Sets of orhtologous protein sequences were generated by mutual-best-hit strategy using full vertebrate genomes available in Ensembl. The scores, described on documentation page, are assigned to each individual residue in a protein, and presented in the form of a table (html or downloadable xls formats) and mapped, when appropriate, onto the related structure (Jmol, Pymol, Chimera).
Abbreviations: Cube-DB
Synonyms: Cube-DB: Detection of Functional Divergence in Human Protein Families
Resource Type: data or information resource, database
Defining Citation: PMID:22139934
Keywords: protein, functional divergence, vertebrate, genome, ortholog, protein sequence, data set, bio.tools
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