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URL: http://spina.sourceforge.net
Proper Citation: SPINA Thyr (RRID:SCR_014352)
Description: Software tool to deliver estimated structure parameters of endocrine feedback control systems in vivo from serum or plasma hormone levels. Used for evaluation of thyroid function. Allows for calculating thyroid maximum secretory capacity (GT or SPINA-GT) and sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr). Binaries are available for Mac OS, Mac OS X, Palm OS, Garnet OS and Windows. For other operating systems, including Linux, Solaris and BSD, SPINA Thyr is available as sourcecode. Building from source requires THINK Pascal (for Mac OS Classic), winsoft PocketStudio (for Palm OS / Garnet OS) or Lazarus/Free Pascal (for Mac OS X, Windows, Linux, BSD and Solaris). Special version of calculation engine is available for modern S implementation, e.g. R.
Abbreviations: SPINA, SPINA Thyr
Synonyms: Structure Parameter Inference Approach, Structure Parameter Inference Approach Thyroid
Resource Type: software resource, standalone software, data analytics software, software application
Defining Citation: PMID:23365787
Keywords: Thyroid function, secretory capacity evaluation, hypothyroidism, thyrotoxicosis, clinical calculator, SPINA-GT, SPINA-GD, total deiodinase activity
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