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Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285)Copy Citation Copied
URL: http://www.kidneycenter.pitt.edu/cores/single_nephron_core.html
Proper Citation: Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285)
Description: Core that offers functional (in vitro microperfusion of isolated segments, measurements of transepithelial ion/solute fluxes, fluorescence functional imaging of single tubular cells), biochemical (microassays of enzyme/transporter activity), molecular (quantitation and analysis of RNA and protein), and analytical (targeted renal metabolomics of interrelated networks of small molecules) strategies applied to microdissected tubules, single cells, and urinary exosomes to address relevant questions proposed by users. It also provides analytical services for determining concentrations of exogenous pharmacological agents and molecular probes achieved within the tissue of interest.
Resource Type: service resource, resource, access service resource, core facility
Keywords: single nephron, metabolomics, renal cells, cell analysis and function
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