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URL: https://www.themiamiproject.org/research-resources/core-facilities/drug-discovery-core/
Proper Citation: Drug Discovery Core Facility (RRID:SCR_022542)
Description: Core at Miami Project to Cure Paralysis leverages PerkinElmer Opera Phenix Plus high content screening system to provide assay development and phenotypic screening. Facility is also equipped with PerkinElmer Janus G3 liquid handler, featuring modular and variable dispense heads, to automate screening workflows and enhance throughput. Core supports phenotypic and target-based assays. Phenotypic assays range from 2D to 3D, widefield to confocal, and antibody to dye based. It collaborates with users to develop customized assays and analytical pipelines tailored to their specific needs. Current specializations include neurite tracing, lipid droplet quantification, cell viability, morphological and kinetic analyses, phagocytosis, cell marker detection, cell adhesion, among others.
Abbreviations: DDC
Synonyms: Miami Project To Cure Paralysis Drug Discovery Core, Drug Discovery Core
Resource Type: service resource, access service resource, core facility
Keywords: USEDit, ABRF, high content screening, liquid handling, biochemical assays, target engagement assays, phenotypic screening, drug discovery
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