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University of Colorado Anschutz Medical Campus Genetically Engineered Murine Models Core Facility (RRID:SCR_025491)Copy Citation Copied
URL: https://medschool.cuanschutz.edu/immunology-and-microbiology/core-labs/gemm-core
Proper Citation: University of Colorado Anschutz Medical Campus Genetically Engineered Murine Models Core Facility (RRID:SCR_025491)
Description: Core provides full-service mouse genetic engineering support to researchers.Helps to select model for your research program, design and build any requisite constructs and reagents, and produce live mice. The most popular requests are for CRISPR-based gene edited mice and transgenic mice. Services include creation of engineered alleles for knockouts, conditional knockouts, SNP knockins, tag and marker insertions, deletions of up to 300kb, duplications, and transgenic alleles. These novel mouse models have been made on a wide spectrum of genetic background strains, including but not limited to C57BL/6J, C57BL/6N, NOD, BALB/cJ, FVB/Crl, NSGS, various 129 substrains, collaborative cross strains, and on mice that are already genetically modified. Breeding and genotyping program supports breeding to establish germline transmission and can also create cohorts for investigators. Provides strain cryopreservation, rederivation and rescue services, as well as cryostorage.
Abbreviations: GEMM
Synonyms: , Genetically Engineered Murine Models (GEMM) Core, University of Colorado Anschutz Medical Campus Genetically Engineered Murine Models (GEMM) Core
Resource Type: service resource, access service resource, core facility
Keywords: ABRF, Breeding and genotyping program, mouse genetic engineering support, CRISPR-based gene edited mice, transgenic mice,
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