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URL: https://caravagnalab.github.io/CNAqc/
Proper Citation: CNAqc (RRID:SCR_027066)
Description: Software package to quality control bulk cancer sequencing data. Used to visualise and manipulate i) somatic mutation data of both single-nucleotide variants and insertion-deletions, ii) allele-specific Copy Number Alterations (CNAs) and iii) tumour purity estimates. Used to validate copy number segmentations against variant allele frequencies of somatic mutations. Provides automatic copy number calling pipeline. Provides also algorithms to phase mutation multiplicities against CNAs and estimate Cancer Cell Fractions (CCFs) with their uncertainty.
Resource Type: software toolkit, software resource
Keywords: quality control bulk cancer sequencing datavalidate copy number segmentations, variant allele frequencies, somatic mutations, automatic copy number,
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