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URL: https://github.com/ShixiangWang/sigflow
Proper Citation: SigFlow (RRID:SCR_028486)
Description: Software automated and comprehensive pipeline for cancer genome mutational signature analysis. Provides one-stop solution for de novo signature extraction, reference signature fitting, signature stability analysis, sample clustering based on signature exposure in different types of genome DNA alterations including single base substitution, doublet base substitution, small insertion and deletion and copy number alteration. It can auto-extract mutational signatures, fit mutation data to all/specified COSMIC reference signatures (SBS/DBS/INDEL) and run bootstrapping analysis for studying signature stability.
Synonyms: , sigflow, Sigflow
Resource Type: software resource, software toolkit, source code
Defining Citation: PMID:33270873
Keywords: cancer genome mutational signature analysis, cancer genome, mutational signature analysis,
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