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Proper Citation: RRID:MGI:2672936
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased spleen germinal center size, abnormal class switch recombination, abnormal B cell physiology, abnormal Peyer's patch germinal center morphology, decreased IgG2b level, small Peyer's patches, decreased IgG1 level, abnormal B cell number, decreased interleukin-21 secretion, decreased IgA level, decreased CD4-positive, alpha beta T cell number, decreased spleen germinal center number, decreased IgG2c level, abnormal T cell physiology, abnormal immune system physiology, decreased T cell proliferation, abnormal spleen morphology, decreased spleen germinal center number, decreased IgG1 level, decreased IgE level
Affected Gene: Icos
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
