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Proper Citation: RRID:MGI:3619802
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: absent masseter muscle, fusion of basioccipital and basisphenoid bone, absent tympanic ring, persistent truncus arteriosis, retroesophageal right subclavian artery, abnormal aortic arch morphology, small thyroid gland, athymia, skin edema, cleft secondary palate, temporal bone hypoplasia, absent semicircular canals, absent cochlea, pharynx hypoplasia, absent outer ear, absent middle ear ossicles, abnormal endolymphatic duct morphology, hyoid bone hypoplasia, abnormal craniofacial bone morphology, inner ear hypoplasia, otic capsule hypoplasia, absent middle ear ossicles, absent inner ear vestibule, abnormal middle ear morphology, absent outer ear, absent tubotympanic recess, small otic vesicle, abnormal vestibulocochlear ganglion morphology, abnormal pharyngeal pouch morphology, absent inner ear, neonatal lethality, complete penetrance, fusion of basioccipital and basisphenoid bone, cleft secondary palate, neonatal lethality, complete penetrance, absent pterygoid muscle, abnormal cardiac outflow tract development, absent zygomatic arch, absent tympanic ring, otic vesicle hypoplasia, short mandible, absent parathyroid glands, ventricular septal defect
Affected Gene: Tbx1, Foxg1
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No rating or validation information has been found for Foxg1tm1(cre)Skm/Foxg1+; Tbx1tm2.1Bem/Tbx1tm2.2Bem.
No alerts have been found for Foxg1tm1(cre)Skm/Foxg1+; Tbx1tm2.1Bem/Tbx1tm2.2Bem.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI