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Proper Citation: RRID:MGI:3697516
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal respiratory mucosa goblet cell morphology, increased circulating interleukin-4 level, abnormal cytokine secretion, increased circulating tumor necrosis factor level, increased circulating interleukin-6 level, increased circulating interleukin-10 level, absent regulatory T cells, increased eosinophil cell number, increased IgG1 level, increased IgE level, thrombocytopenia, increased circulating interferon-gamma level, increased monocyte cell number, postnatal lethality, complete penetrance, increased circulating interleukin-5 level, increased lymphocyte cell number, increased leukocyte cell number, dermatitis, crypts of Lieberkuhn abscesses, abnormal chemokine level, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, abnormal inflammatory response, anemia, respiratory system inflammation, increased activated T cell number, abnormal lymphocyte physiology, postnatal lethality, complete penetrance, enlarged spleen
Affected Gene: Foxp3
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
