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Proper Citation: RRID:MGI:4352689
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal nitric oxide homeostasis, increased sensitivity to induced morbidity/mortality, abnormal lymph node B cell domain morphology, abnormal metallophilic macrophage morphology, abnormal spleen B cell follicle morphology, abnormal spleen marginal zone macrophage morphology, absent spleen germinal center, decreased B cell number, decreased IgG2a level, decreased interferon-gamma secretion, decreased interleukin-12 secretion, decreased macrophage cell number, decreased spleen germinal center size, increased susceptibility to parasitic infection, intermingled spleen red and white pulp, lymph node hypoplasia, abnormal B cell differentiation, abnormal class switch recombination, abnormal cytotoxic T cell physiology, abnormal lymphocyte morphology
Affected Gene: Bcl3
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Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI
