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Proper Citation: RRID:MGI:4360636
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased body size, decreased bone marrow cell number, arrested T cell differentiation, absent pre-B cells, absent inguinal lymph nodes, absent mesenteric lymph nodes, abnormal gut flora balance, thymus hypoplasia, postnatal lethality, incomplete penetrance, multifocal hepatic necrosis, lung inflammation, intermingled spleen red and white pulp, increased susceptibility to bacterial infection, increased nucleated erythrocyte cell number, increased basophil cell number, extramedullary hematopoiesis, absent cervical lymph nodes, absent axillary lymph nodes, absent Peyer's patches, absent B cells, abnormal thymus morphology, abnormal thymus cortex morphology, enlarged spleen, abnormal spleen morphology, abnormal immune system organ morphology, abnormal definitive hematopoiesis, abnormal erythroid progenitor cell morphology, abnormal eosinophil morphology, abnormal common myeloid progenitor cell morphology, abnormal NK cell morphology, decreased gamma-delta intraepithelial T cell number
Affected Gene: Ikzf1
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Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI
