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Proper Citation: RRID:MGI:4831132
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased interferon-gamma secretion, decreased splenocyte proliferation, decreased interferon-gamma secretion, decreased T cell proliferation, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased interleukin-6 secretion, increased interferon-gamma secretion, hepatic necrosis, increased circulating alanine transaminase level, increased hepatocyte apoptosis, liver hemorrhage, increased physiological sensitivity to xenobiotic, increased tumor necrosis factor secretion, abnormal lipid homeostasis, impaired macrophage chemotaxis, abnormal cholesterol homeostasis, impaired macrophage chemotaxis, abnormal microglial cell physiology, decreased airway responsiveness, decreased susceptibility to type I hypersensitivity reaction, abnormal immune serum protein physiology, abnormal macrophage chemotaxis, decreased inflammatory response, decreased common myeloid progenitor cell number, impaired macrophage chemotaxis, decreased interleukin-2 secretion, abnormal Langerhans cell physiology
Affected Gene: Ccr2
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No rating or validation information has been found for Ccr2tm1Ifc/Ccr2tm1Ifc.
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Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI
