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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=194
Proper Citation: RRID:MMRRC_000194-UCD
Description: Mus musculus with name STOCK Itgb8tm1Lfr/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cell Biology, Developmental Biology, Hematology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: cleft palate [MP:0000111]| abnormal angiogenesis [MP:0000260]| failure of vascular branching [MP:0000264]| abnormal heart morphology [MP:0000266]| absent floor plate [MP:0000926]| abnormal cardiovascular system physiology [MP:0001544]| abnormal blood vessel morphology [MP:0001614]| decreased embryo size [MP:0001698]| abnormal placenta morphology [MP:0001711]| abnormal visceral yolk sac morphology [MP:0001718]| pale yolk sac [MP:0001722]| hydroencephaly [MP:0001891]| intracranial hemorrhage [MP:0001915]| intracerebral hemorrhage [MP:0001916]| abnormal extraembryonic tissue morphology [MP:0002086]| no abnormal phenotype detected [MP:0002169]| abnormal astrocyte morphology [MP:0002182]| abnormal chorioallantoic fusion [MP:0002824]| impaired basement membrane formation [MP:0003044]| abnormal vitelline vasculature morphology [MP:0003229]| abnormal placenta vasculature [MP:0003231]| abnormal radial glial cell morphology [MP:0003648]| abnormal capillary morphology [MP:0003658]| abnormal embryonic/fetal subventricular zone morphology [MP:0004274]| abnormal brain vasculature morphology [MP:0004950]| hemopericardium [MP:0005244]| abnormal heart ventricle morphology [MP:0005294]| abnormal vascular endothelial cell morphology [MP:0006055]| increased vascular endothelial cell number [MP:0006056]| abnormal placental labyrinth vasculature morphology [MP:0008803]| palatal shelves fail to meet at midline [MP:0009888]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011108]| embryonic lethality during organogenesis [MP:0011380]| incomplete penetrance [MP:0011523]| enlarged brain ventricles [MP:0012501]
Affected Gene: Itgb8
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
