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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=221
Proper Citation: RRID:MMRRC_000221-MU
Description: Mus musculus with name JU.Cg-Ay/a/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Developmental Biology, Diabetes, Endocrine Deficiency, Hematology, Immunology and Inflammation, Internal/Organ, Metabolism, Models for Human Disease, Neurobiology, Reproduction, Research Tools, Sensorineural; Mutation Type: Spontaneous Mutation ; Collection: Mammalian Pigmentation
Phenotype: increased brown adipose tissue amount [MP:0000005]| increased monocyte cell number [MP:0000220]| increased body length [MP:0001257]| increased body weight [MP:0001260]| obese [MP:0001261]| decreased body weight [MP:0001262]| hyperactivity [MP:0001399]| hypoactivity [MP:0001402]| abnormal eating behavior [MP:0001431]| polyphagia [MP:0001433]| increased circulating triglyceride level [MP:0001552]| hyperglycemia [MP:0001559]| increased urine glucose level [MP:0001759]| abnormal inflammatory response [MP:0001845]| decreased incidence of induced tumors [MP:0002053]| increased circulating insulin level [MP:0002079]| abnormal lipid homeostasis [MP:0002118]| abnormal kidney morphology [MP:0002135]| abnormal renal tubule morphology [MP:0002703]| dilated renal tubules [MP:0002705]| variable body spotting [MP:0002940]| increased liver weight [MP:0002981]| yellow coat color [MP:0003136]| decreased liver weight [MP:0003402]| maternal effect [MP:0003718]| abnormal hair follicle melanogenesis [MP:0004382]| decreased adiponectin level [MP:0004893]| increased circulating cholesterol level [MP:0005178]| abnormal pancreatic islet morphology [MP:0005215]| glomerulosclerosis [MP:0005264]| improved glucose tolerance [MP:0005292]| impaired glucose tolerance [MP:0005293]| abnormal renal glomerulus morphology [MP:0005325]| insulin resistance [MP:0005331]| atherosclerotic lesions [MP:0005338]| darkened coat color [MP:0005409]| abnormal food intake [MP:0005449]| increased susceptibility to weight gain [MP:0005455]| increased percent body fat/body weight [MP:0005458]| decreased circulating glucose level [MP:0005560]| increased circulating leptin level [MP:0005669]| embryonic lethality [MP:0008762]| degranulated pancreatic beta cells [MP:0009255]| increased gonadal fat pad weight [MP:0009285]| increased inguinal fat pad weight [MP:0009292]| increased retroperitoneal fat pad weight [MP:0009304]| increased total body fat amount [MP:0010024]| embryonic lethality at implantation [MP:0011093]| complete penetrance [MP:0011339]| abnormal glomerular mesangium morphology [MP:0011353]| expanded mesangial matrix [MP:0011402]| renal cast [MP:0011409]| increased renal glomerulus basement membrane thickness [MP:0011939]| increased food intake [MP:0030050]
Affected Gene: a
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
