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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=434
Proper Citation: RRID:MMRRC_000434-UNC
Description: Mus musculus with name STOCK Pdx1tm2Cvw/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Diabetes, Endocrine Deficiency; Mutation Type: Targeted Mutation ; Collection: BCBC-Beta Cell Biology Consortium
Phenotype: sparse hair [MP:0000416]| abnormal stomach morphology [MP:0000470]| abnormal foregut morphology [MP:0000474]| abnormal intestine morphology [MP:0000477]| abnormal small intestine morphology [MP:0000496]| abnormal liver development [MP:0000596]| thin skin [MP:0001199]| decreased body weight [MP:0001262]| dehydration [MP:0001429]| postnatal growth retardation [MP:0001732]| increased glucagon secretion [MP:0002710]| decreased circulating insulin level [MP:0002727]| abnormal bile duct development [MP:0002929]| decreased insulin secretion [MP:0003059]| abnormal duodenum morphology [MP:0003271]| exocrine pancreatic insufficiency [MP:0003335]| abnormal pancreatic beta cell physiology [MP:0003562]| absent pancreas [MP:0003655]| abnormal pancreas development [MP:0003934]| abnormal enteroendocrine cell morphology [MP:0004141]| abnormal pancreatic islet morphology [MP:0005215]| impaired glucose tolerance [MP:0005293]| pancreatic islet hyperplasia [MP:0005491]| increased circulating glucose level [MP:0005559]| abnormal mitochondrial physiology [MP:0006036]| abnormal pancreatic duct morphology [MP:0009143]| abnormal pancreatic acinar cell morphology [MP:0009146]| abnormal pancreatic beta cell differentiation [MP:0009175]| distended stomach [MP:0009511]| abnormal pyloric sphincter morphology [MP:0009861]| abnormal stomach pyloric region morphology [MP:0010785]| abnormal stomach enteroendocrine cell morphology [MP:0010803]| abnormal tricarboxylic acid cycle [MP:0010958]| postnatal lethality [MP:0011085]| complete penetrance [MP:0014125]
Affected Gene: Pdx1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
