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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=442
Proper Citation: RRID:MMRRC_000442-MU
Description: Mus musculus with name B6.129S7-Chrna5tm1Mdb Chrnb4tm1Mdb/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: delayed ear emergence [MP:0000054]| delayed hair appearance [MP:0000422]| abnormal urinary bladder morphology [MP:0000538]| distended urinary bladder [MP:0000539]| abnormal urinary bladder urothelium morphology [MP:0000540]| postnatal growth retardation [MP:0001732]| increased susceptibility to bacterial infection [MP:0002412]| mydriasis [MP:0002546]| decreased susceptibility to pharmacologically induced seizures [MP:0002887]| urinary incontinence [MP:0003280]| intestinal hypoperistalsis [MP:0003290]| abnormal single cell response [MP:0003463]| eyelids fail to open [MP:0005176]| narrow eye opening [MP:0005287]| impaired pupillary reflex [MP:0006243]| abnormal autonomic nervous system physiology [MP:0006276]| urinary bladder inflammation [MP:0009646]| abnormal urinary bladder physiology [MP:0010386]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011625]| decreased susceptibility to pharmacologically induced seizures [MP:0002887]
Affected Gene: |Chrnb4||Chrna5
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
