Searching the RRID Resource Information Network
Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=11489
Proper Citation: RRID:MMRRC_011489-UNC
Description: Mus musculus with name C.129-Cd40tm1Kik Cd86tm2Shr Cd80tm1Shr/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Dermatology, Immunology and Inflammation, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased cell proliferation [MP:0000352]| abnormal spleen morphology [MP:0000689]| decreased IgG level [MP:0001805]| brain inflammation [MP:0001847]| abnormal lymph node B cell domain morphology [MP:0002344]| abnormal T cell physiology [MP:0002444]| abnormal immunoglobulin level [MP:0002490]| increased IgM level [MP:0002494]| abnormal cytokine secretion [MP:0003009]| insulitis [MP:0004031]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased regulatory T cell number [MP:0004974]| decreased double-positive T cell number [MP:0005092]| decreased B cell proliferation [MP:0005093]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005623]| abnormal meninges morphology [MP:0006387]| abnormal T cell number [MP:0008495]| decreased IgG1 level [MP:0008496]| decreased IgG2a level [MP:0008502]| increased IgG3 level [MP:0008560]| increased tumor necrosis factor secretion [MP:0008566]| increased interferon-gamma secretion [MP:0008688]| decreased interleukin-2 secretion [MP:0009023]| paresis [MP:0000754]| hindlimb paralysis [MP:0000755]| demyelination [MP:0000921]| abnormal dorsal root ganglion morphology [MP:0000961]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| brain inflammation [MP:0001847]| muscular atrophy [MP:0002269]| abnormal nervous system morphology [MP:0003632]| increased autoantibody level [MP:0003725]| abnormal myelin sheath morphology [MP:0003871]| abnormal ventral spinal root morphology [MP:0003993]| abnormal dorsal spinal root morphology [MP:0003994]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased regulatory T cell number [MP:0004974]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| abnormal action potential [MP:0005402]| abnormal nerve conduction [MP:0005403]| absent spleen germinal center [MP:0008474]| increased tumor necrosis factor secretion [MP:0008560]| decreased tumor necrosis factor secretion [MP:0008561]| increased interferon-gamma secretion [MP:0008566]| decreased interleukin-12 secretion [MP:0008664]| decreased nerve conduction velocity [MP:0008814]| decreased grip strength [MP:0010053]| decreased bone mineral density [MP:0000063]| decreased neutrophil cell number [MP:0000222]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| abnormal humoral immune response [MP:0001800]| decreased IgA level [MP:0001807]| no abnormal phenotype detected [MP:0002169]| abnormal thymus medulla morphology [MP:0002375]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| decreased IgE level [MP:0002492]| glomerulonephritis [MP:0002743]| increased urine protein level [MP:0002962]| increased anti-double stranded DNA antibody level [MP:0004762]| abnormal class switch recombination [MP:0004816]| decreased B cell number [MP:0005017]| decreased susceptibility to type II hypersensitivity reaction [MP:0005612]| decreased cerebral infarction size [MP:0006058]| increased follicular B cell number [MP:0008173]| absent germinal center B cells [MP:0008179]| increased marginal zone B cell number [MP:0008181]| increased transitional stage B cell number [MP:0008189]| abnormal B cell activation [MP:0008217]| absent spleen germinal center [MP:0008474]| decreased IgG1 level [MP:0008495]| decreased IgG2a level [MP:0008496]| decreased IgG2b level [MP:0008497]| decreased IgG3 level [MP:0008498]| abnormal thymus epithelium morphology [MP:0009544]| decreased platelet aggregation [MP:0009549]| decreased trabecular bone mass [MP:0010873]| decreased compact bone mass [MP:0010962]| renal glomerular immunoglobulin deposits [MP:0020519]
Affected Gene: |Cd40||Cd80||Cd86
Expand AllWe found {{ ctrl2.mentions.all_count }} mentions in open access literature.
We have not found any literature mentions for this resource.
We are searching literature mentions for this resource.
Most recent articles:
{{ mention._source.dc.creators[0].familyName }} {{ mention._source.dc.creators[0].initials }}, et al. ({{ mention._source.dc.publicationYear }}) {{ mention._source.dc.title }} {{ mention._source.dc.publishers[0].name }}, {{ mention._source.dc.publishers[0].volume }}({{ mention._source.dc.publishers[0].issue }}), {{ mention._source.dc.publishers[0].pagination }}. (PMID:{{ mention._id.replace('PMID:', '') }})
Check
for all resource mentions.
A list of researchers who have used the resource and an author search tool
A list of researchers who have used the resource and an author search tool. This is available for resources that have literature mentions.
No rating or validation information has been found for C.129-Cd40tm1Kik Cd86tm2Shr Cd80tm1Shr/Mmnc.
No alerts have been found for C.129-Cd40tm1Kik Cd86tm2Shr Cd80tm1Shr/Mmnc.
Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
