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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=11529
Proper Citation: RRID:MMRRC_011529-UNC
Description: Mus musculus with name B6.129-Hbegftm1Dcl/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Cell Biology, Developmental Biology, Diabetes, Immunology and Inflammation, Internal/Organ, Models for Human Disease, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: enlarged heart [MP:0000274]| pulmonary hypoplasia [MP:0001178]| decreased body weight [MP:0001262]| abnormal atrial thrombosis [MP:0001855]| postnatal lethality [MP:0002082]| premature death [MP:0002083]| abnormal pulmonary alveolus morphology [MP:0002270]| abnormal type II pneumocyte morphology [MP:0002275]| abnormal atrioventricular valve morphology [MP:0002745]| abnormal semilunar valve morphology [MP:0002746]| abnormal pulmonary valve morphology [MP:0002748]| increased heart weight [MP:0002833]| cardiac fibrosis [MP:0003141]| ectopic cartilage [MP:0003869]| dilated heart left atrium [MP:0004063]| decreased ventricle muscle contractility [MP:0005598]| impaired lung alveolus development [MP:0006027]| aortic valve stenosis [MP:0006117]| pulmonary valve stenosis [MP:0006128]| aorta dilation [MP:0010574]| enlarged aortic valve [MP:0010591]| enlarged pulmonary valve [MP:0010600]
Affected Gene: Hbegf
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
