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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=11530
Proper Citation: RRID:MMRRC_011530-UNC
Description: Mus musculus with name B6;129-Hbegftm1Dcl/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Cell Biology, Developmental Biology, Diabetes, Immunology and Inflammation, Internal/Organ, Models for Human Disease, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: enlarged heart [MP:0000274]| pulmonary hypoplasia [MP:0001178]| decreased body weight [MP:0001262]| abnormal atrial thrombosis [MP:0001855]| postnatal lethality [MP:0002082]| premature death [MP:0002083]| abnormal pulmonary alveolus morphology [MP:0002270]| abnormal type II pneumocyte morphology [MP:0002275]| abnormal atrioventricular valve morphology [MP:0002745]| abnormal semilunar valve morphology [MP:0002746]| abnormal pulmonary valve morphology [MP:0002748]| increased heart weight [MP:0002833]| cardiac fibrosis [MP:0003141]| ectopic cartilage [MP:0003869]| dilated heart left atrium [MP:0004063]| decreased ventricle muscle contractility [MP:0005598]| impaired lung alveolus development [MP:0006027]| aortic valve stenosis [MP:0006117]| pulmonary valve stenosis [MP:0006128]| aorta dilation [MP:0010574]| enlarged aortic valve [MP:0010591]| enlarged pulmonary valve [MP:0010600]
Affected Gene: Hbegf
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)