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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=11535
Proper Citation: RRID:MMRRC_011535-UNC
Description: Mus musculus with name B6;129-Egftm1Dle Tgfatm1Unc/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cell Biology, Dermatology, Developmental Biology, Immunology and Inflammation, Internal/Organ, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal adipose tissue distribution [MP:0000013]| abnormal hair follicle morphology [MP:0000377]| abnormal hair follicle orientation [MP:0000383]| waved hair [MP:0000410]| alopecia [MP:0000414]| abnormal small intestine morphology [MP:0000496]| abnormal branching of the mammary ductal tree [MP:0000662]| dermatitis [MP:0001194]| spontaneous skin ulceration [MP:0001209]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| curly vibrissae [MP:0001274]| kinked vibrissae [MP:0001278]| microphthalmia [MP:0001297]| eyelids open at birth [MP:0001302]| cataract [MP:0001304]| corneal opacity [MP:0001314]| corneal scarring [MP:0001316]| abnormal iris morphology [MP:0001322]| abnormal eyelid morphology [MP:0001340]| disheveled coat [MP:0001511]| postnatal growth retardation [MP:0001732]| abnormal eye morphology [MP:0002092]| duodenal lesions [MP:0002580]| abnormal ileum morphology [MP:0002581]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal eyelid aperture [MP:0003671]| abnormal hair shaft morphology [MP:0003809]| abnormal hair medulla [MP:0003812]| absent Descemet membrane [MP:0004285]| small mandible [MP:0004592]| abnormal small intestine crypts of Lieberkuhn morphology [MP:0004841]| abnormal anterior eye segment morphology [MP:0005193]| abnormal mammary gland growth during pregnancy [MP:0006269]| ruptured lens capsule [MP:0008841]| retinal neovascularization [MP:0008852]| abnormal eyelid development [MP:0009651]| absent eye anterior chamber [MP:0010709]| Meibomian gland hypoplasia [MP:0013389]| eyelid hyperplasia [MP:0013396]| hypolactation [MP:0013716]| orbicularis oculi muscle hypoplasia [MP:0030175]| waved hair [MP:0000410]| alopecia [MP:0000414]| abnormal small intestine morphology [MP:0000496]| abnormal branching of the mammary ductal tree [MP:0000662]| dermatitis [MP:0001194]| spontaneous skin ulceration [MP:0001209]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| curly vibrissae [MP:0001274]| microphthalmia [MP:0001297]| eyelids open at birth [MP:0001302]| corneal opacity [MP:0001314]| postnatal growth retardation [MP:0001732]| no abnormal phenotype detected [MP:0002169]| duodenal lesions [MP:0002580]| abnormal ileum morphology [MP:0002581]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal small intestine crypts of Lieberkuhn morphology [MP:0004841]| abnormal mammary gland growth during pregnancy [MP:0006269]| hypolactation [MP:0013716]
Affected Gene: |Egf||Tgfa
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)