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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=14244
Proper Citation: RRID:MMRRC_014244-UCD
Description: Mus musculus with name STOCK Pik3r1tm2Dfr/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cell Biology, Developmental Biology, Diabetes, Hematology, Immunology and Inflammation, Metabolism; Mutation Type: Targeted Mutation ; Collection:
Phenotype: hypoglycemia [MP:0000189]| decreased body size [MP:0001265]| hepatic necrosis [MP:0001654]| arrested B cell differentiation [MP:0001802]| abnormal glucose homeostasis [MP:0002078]| abnormal B cell differentiation [MP:0002144]| decreased circulating insulin level [MP:0002727]| dystrophic cardiac calcinosis [MP:0002837]| abnormal brown adipose tissue morphology [MP:0002971]| decreased B cell proliferation [MP:0005093]| improved glucose tolerance [MP:0005292]| increased pro-B cell number [MP:0008186]| decreased pre-B cell number [MP:0008209]| decreased mature B cell number [MP:0008211]| decreased immature B cell number [MP:0008215]| increased B cell apoptosis [MP:0008782]| increased skeletal muscle fiber size [MP:0009399]| postnatal lethality [MP:0011086]| incomplete penetrance [MP:0011099]| lethality throughout fetal growth and development [MP:0012080]
Affected Gene: Pik3r1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)