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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15388
Proper Citation: RRID:MMRRC_015388-UNC
Description: Mus musculus with name STOCK Dicer1tm1Tara/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Dermatology, Developmental Biology, Diabetes, Endocrine Deficiency, Hematology, Immunology and Inflammation, Internal/Organ, Metabolism, Neurobiology, Reproduction, Sensorineural, Virology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal coat/ hair morphology [MP:0000367]| abnormal hair follicle morphology [MP:0000377]| abnormal thymus morphology [MP:0000703]| decreased body size [MP:0001265]| increased metastatic potential [MP:0001272]| dehydration [MP:0001429]| abnormal thymus involution [MP:0001824]| increased carcinoma incidence [MP:0002038]| premature death [MP:0002083]| abnormal vibrissa morphology [MP:0002098]| abnormal thymus cortex morphology [MP:0002371]| abnormal thymus medulla morphology [MP:0002375]| epidermal cyst [MP:0003414]| abnormal oviduct morphology [MP:0003574]| increased ovarian carcinoma incidence [MP:0003579]| abnormal hair follicle development [MP:0003704]| increased susceptibility to induced arthritis [MP:0003724]| abnormal thymus physiology [MP:0003763]| abnormal positive T cell selection [MP:0004919]| ascites [MP:0005324]| abnormal skin physiology [MP:0005501]| increased apoptosis [MP:0006042]| decreased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008079]| decreased CD8-positive [MP:0009544]| alpha-beta T cell number [MP:0009931]| abnormal thymus epithelium morphology [MP:0011085]
Affected Gene: Dicer1
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
