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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=16132
Proper Citation: RRID:MMRRC_016132-UCD
Description: Mus musculus with name FVB;129S6-Foxo3tm1.1Rdp/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Dermatology, Diabetes, Endocrine Deficiency, Hematology, Metabolism, Models for Human Disease, Reproduction; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal oocyte morphology [MP:0001125]| abnormal ovarian folliculogenesis [MP:0001130]| abnormal ovarian follicle morphology [MP:0001131]| dermatitis [MP:0001194]| anemia [MP:0001577]| hemolytic anemia [MP:0001585]| suppressed circulating follicle stimulating hormone level [MP:0001749]| increased circulating follicle stimulating hormone level [MP:0001750]| increased circulating luteinizing hormone level [MP:0001751]| reduced female fertility [MP:0001923]| abnormal estrous cycle [MP:0001927]| ovary cysts [MP:0002016]| increased tumor incidence [MP:0002020]| increased pituitary adenoma incidence [MP:0002041]| increased lung adenoma incidence [MP:0002048]| premature death [MP:0002083]| reticulocytosis [MP:0002640]| decreased circulating luteinizing hormone level [MP:0002773]| absent ovarian follicles [MP:0002777]| increased prolactinoma incidence [MP:0003505]| increased hemangiosarcoma incidence [MP:0003667]| enlarged ovary [MP:0004832]| increased circulating estradiol level [MP:0005182]| impaired glucose tolerance [MP:0005293]| abnormal circulating hormone level [MP:0005418]| increased ovary tumor incidence [MP:0008000]| early reproductive senescence [MP:0008995]| absent estrous cycle [MP:0009009]| increased ovarian teratoma incidence [MP:0009442]| decreased tumor latency [MP:0010308]| decreased primordial ovarian follicle number [MP:0011121]| decreased primary ovarian follicle number [MP:0011125]| increased granulosa cell tumor incidence [MP:0012411]| increased Harderian gland tumor incidence [MP:0012437]
Affected Gene: Foxo3
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
