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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=16831
Proper Citation: RRID:MMRRC_016831-MU
Description: Mus musculus with name B6.129P2-Xpatm1Hvs/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection: CMGCC
Phenotype: abnormal abdominal fat pad morphology [MP:0000010]| abnormal adipose tissue distribution [MP:0000013]| osteoporosis [MP:0000066]| kyphosis [MP:0000160]| hypoglycemia [MP:0000189]| abnormal cell death [MP:0000313]| abnormal hair follicle morphology [MP:0000377]| abnormal cranium morphology [MP:0000438]| long limbs [MP:0000548]| small liver [MP:0000601]| tremors [MP:0000745]| abnormal telencephalon morphology [MP:0000787]| abnormal cerebral cortex morphology [MP:0000788]| dilated lateral ventricles [MP:0000825]| Purkinje cell degeneration [MP:0000876]| abnormal Purkinje cell morphology [MP:0000877]| reddish skin [MP:0001190]| scaly skin [MP:0001192]| abnormal epidermal layer morphology [MP:0001216]| hyperkeratosis [MP:0001242]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| corneal opacity [MP:0001314]| abnormal retina morphology [MP:0001325]| retinal degeneration [MP:0001326]| ataxia [MP:0001393]| hyperactivity [MP:0001399]| impaired coordination [MP:0001405]| abnormal gait [MP:0001406]| short stride length [MP:0001407]| impaired limb coordination [MP:0001524]| impaired balance [MP:0001525]| anemia [MP:0001577]| impaired hematopoiesis [MP:0001606]| postnatal growth retardation [MP:0001732]| skin edema [MP:0001786]| acanthosis [MP:0001874]| increased cellular sensitivity to gamma-irradiation [MP:0002007]| increased incidence of induced tumors [MP:0002021]| seizures [MP:0002064]| premature death [MP:0002083]| disproportionate dwarf [MP:0002427]| hepatic steatosis [MP:0002628]| increased thigmotaxis [MP:0002797]| increased cellular sensitivity to X-ray irradiation [MP:0002879]| testicular atrophy [MP:0003205]| neuron degeneration [MP:0003224]| astrocytosis [MP:0003354]| pallor [MP:0003717]| abnormal retinal outer nuclear layer morphology [MP:0003731]| abnormal retinal inner nuclear layer morphology [MP:0003733]| premature aging [MP:0003786]| abnormal dorsal striatum morphology [MP:0004102]| muscle hypertonia [MP:0004143]| fetal growth retardation [MP:0004201]| abnormal limb posture [MP:0004263]| increased incidence of tumors by chemical induction [MP:0004499]| increased incidence of tumors by UV-induction [MP:0004501]| cachexia [MP:0005150]| dystonia [MP:0005323]| axon degeneration [MP:0005405]| abnormal cell physiology [MP:0005621]| thin cerebral cortex [MP:0006254]| abnormal epiphyseal plate morphology [MP:0006395]| increased cellular sensitivity to ultraviolet irradiation [MP:0008410]| decreased cellular sensitivity to ultraviolet irradiation [MP:0008411]| increased cellular sensitivity to oxidative stress [MP:0008412]| slow postnatal weight gain [MP:0008489]| abnormal neocortex morphology [MP:0008547]| microgliosis [MP:0008918]| abnormal base-excision repair [MP:0009796]| increased urinary system tumor incidence [MP:0010289]| increased liver glycogen level [MP:0010400]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011088]| neonatal lethality [MP:0011090]| incomplete penetrance [MP:0011108]| perinatal lethality [MP:0011174]| incomplete penetrance [MP:0030003]
Affected Gene: Xpa
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
