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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=17243
Proper Citation: RRID:MMRRC_017243-UNC
Description: Mus musculus with name C.129(Cg)-Rag1tm1Bal Igk-Jtm2Mwg Igh-Jtm1(3H9-VDJ)Mwg/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Immunology and Inflammation, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal immature B cell morphology [MP:0005022]| abnormal B cell receptor editing [MP:0008766]| arrested T cell differentiation [MP:0001825]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| premature death [MP:0002083]| abnormal kidney morphology [MP:0002135]| abnormal CD4-positive [MP:0002432]| alpha beta T cell morphology [MP:0002599]| increased mean platelet volume [MP:0002703]| abnormal renal tubule morphology [MP:0002962]| increased urine protein level [MP:0003179]| thrombocytopenia [MP:0004505]| decreased renal glomerulus number [MP:0005048]| abnormal thrombosis [MP:0008075]| decreased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0009446]| increased CD8-positive [MP:0009549]
Affected Gene: |Igk-J||||Rag1
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No rating or validation information has been found for C.129(Cg)-Rag1tm1Bal Igk-Jtm2Mwg Igh-Jtm1(3H9-VDJ)Mwg/Mmnc.
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
