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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=30665
Proper Citation: RRID:MMRRC_030665-MU
Description: Mus musculus with name B6;129S1-Tal1tm2Wehi/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Hematology, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal erythropoiesis [MP:0000245]| abnormal heart development [MP:0000267]| distended pericardium [MP:0000292]| decreased bone marrow cell number [MP:0000333]| anemia [MP:0001577]| impaired hematopoiesis [MP:0001606]| abnormal blood vessel morphology [MP:0001614]| absent vitelline blood vessels [MP:0001719]| absent visceral yolk sac blood islands [MP:0001721]| disorganized yolk sac vascular plexus [MP:0001723]| embryonic growth arrest [MP:0001730]| pericardial edema [MP:0001787]| abnormal bone marrow morphology [MP:0002397]| abnormal megakaryocyte progenitor cell morphology [MP:0002413]| abnormal proerythroblast morphology [MP:0002416]| abnormal megakaryocyte morphology [MP:0002417]| abnormal vein morphology [MP:0002725]| thrombocytopenia [MP:0003179]| increased neuron apoptosis [MP:0003203]| abnormal embryonic hematopoiesis [MP:0003396]| dilated dorsal aorta [MP:0004068]| hypoxia [MP:0005039]| abnormal splenic cell ratio [MP:0008826]| delayed heart looping [MP:0009328]| embryonic lethality during organogenesis [MP:0011098]
Affected Gene: Tal1
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
