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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=32042
Proper Citation: RRID:MMRRC_032042-JAX
Description: Mus musculus with name CBA.129S4(B6)-C3tm1Hrc/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection:
Phenotype: increased brown adipose tissue amount [MP:0000005]| dystrophic muscle [MP:0000752]| abnormal skeletal muscle morphology [MP:0000759]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| polyphagia [MP:0001433]| increased circulating free fatty acid level [MP:0001554]| extended life span [MP:0001661]| decreased white adipose tissue amount [MP:0001783]| decreased IgM level [MP:0001806]| abnormal glucose homeostasis [MP:0002078]| abnormal lipid homeostasis [MP:0002118]| increased susceptibility to bacterial infection [MP:0002412]| abnormal complement pathway [MP:0002471]| impaired complement alternative pathway [MP:0002472]| increased IgG level [MP:0002493]| increased IgM level [MP:0002494]| decreased circulating triglyceride level [MP:0002644]| decreased circulating insulin level [MP:0002727]| skeletal muscle interstitial fibrosis [MP:0003851]| abnormal physical strength [MP:0004262]| abnormal oxygen consumption [MP:0005288]| increased triglyceride level [MP:0005317]| abnormal intestinal lipid absorption [MP:0005342]| abnormal energy expenditure [MP:0005450]| abnormal platelet physiology [MP:0005464]| decreased liver regeneration [MP:0005517]| decreased circulating glucose level [MP:0005560]| decreased circulating leptin level [MP:0005668]| decreased total body fat amount [MP:0010025]
Affected Gene: C3
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
