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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=34667
Proper Citation: RRID:MMRRC_034667-UNC
Description: Mus musculus with name B6NCrl.FRA(Cg)-Smpd3fro/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Developmental Biology, Models for Human Disease; Mutation Type: chemically induced mutation ; Collection:
Phenotype: delayed bone ossification [MP:0000060]| decreased bone mineral density [MP:0000063]| abnormal long bone metaphysis morphology [MP:0000133]| abnormal scapula morphology [MP:0000149]| abnormal rib morphology [MP:0000150]| abnormal cartilage development [MP:0000164]| abnormal tibia morphology [MP:0000558]| abnormal femur morphology [MP:0000559]| overexpanded pulmonary alveoli [MP:0001183]| decreased body length [MP:0001258]| decreased body size [MP:0001265]| abnormal lipid level [MP:0001547]| cyanosis [MP:0001575]| reduced fertility [MP:0001921]| respiratory distress [MP:0001954]| emphysema [MP:0001958]| abnormal limb morphology [MP:0002109]| abnormal limb bone morphology [MP:0002115]| abnormal fibula morphology [MP:0002187]| abnormal pulmonary alveolus morphology [MP:0002270]| abnormal bone mineralization [MP:0002896]| increased circulating parathyroid hormone level [MP:0002904]| short femur [MP:0003109]| increased width of hypertrophic chondrocyte zone [MP:0003408]| abnormal long bone morphology [MP:0003723]| abnormal alveolar process morphology [MP:0004189]| short humerus [MP:0004351]| bowed tibia [MP:0004358]| short ulna [MP:0004359]| bowed ulna [MP:0004361]| bowed humerus [MP:0004373]| bowed radius [MP:0004374]| abnormal pubis morphology [MP:0004506]| abnormal ischium morphology [MP:0004507]| short ribs [MP:0004672]| rib fractures [MP:0004675]| decreased length of long bones [MP:0004686]| abnormal osteoblast morphology [MP:0004986]| abnormal ulna morphology [MP:0005108]| abnormal humerus morphology [MP:0005296]| abnormal clavicle morphology [MP:0005298]| abnormal perichondrium morphology [MP:0006322]| abnormal epiphyseal plate morphology [MP:0006395]| abnormal bone ossification [MP:0008271]| abnormal sternum ossification [MP:0008277]| decreased survivor rate [MP:0008770]| decreased bone trabecula number [MP:0010869]| increased lung compliance [MP:0010895]| abnormal periosteum morphology [MP:0010971]| postnatal lethality [MP:0011086]| incomplete penetrance [MP:0030542]
Affected Gene: Smpd3
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
