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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36421
Proper Citation: RRID:MMRRC_036421-UCD
Description: Mus musculus with name C57BL/6JSfdAnu-Muc2wnn/AnuApbMmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: chemically induced mutation ; Collection: NHMRC Australian PhenomeBank
Phenotype: decreased hematocrit [MP:0000208]| increased leukocyte cell number [MP:0000218]| abnormal intestine morphology [MP:0000477]| rectal prolapse [MP:0000493]| abnormal colon morphology [MP:0000495]| abnormal intestinal mucosa morphology [MP:0000511]| intestinal ulcer [MP:0000512]| increased circulating triglyceride level [MP:0001552]| abnormal digestive system physiology [MP:0001663]| abnormal intestinal absorption [MP:0001666]| premature death [MP:0002083]| colitis [MP:0002816]| melena [MP:0003292]| rectal hemorrhage [MP:0003293]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal large intestine crypts of Lieberkuhn morphology [MP:0004842]| increased lymphocyte cell number [MP:0005013]| diarrhea [MP:0005036]| increased susceptibility to induced colitis [MP:0008537]| increased tumor necrosis factor secretion [MP:0008560]| increased interferon-gamma secretion [MP:0008566]| increased interleukin-1 beta secretion [MP:0008657]| increased interleukin-13 secretion [MP:0008672]| abnormal enterocyte proliferation [MP:0008883]| increased enterocyte apoptosis [MP:0008885]| abnormal endoplasmic reticulum morphology [MP:0009378]| ileum inflammation [MP:0009482]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009766]| abnormal intestine physiology [MP:0010155]| increased susceptibility to weight loss [MP:0010180]| dilated mitochondria [MP:0011632]| abnormal mitochondrial crista morphology [MP:0011635]| decreased colon length [MP:0013956]| increased endoplasmic reticulum stress [MP:0020354]
Affected Gene: Muc2
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
